Thursday 22 March 2012

Minocycline Extended-Release Tablets



Pronunciation: MIN-oh-SYE-kleen
Generic Name: Minocycline
Brand Name: Solodyn


Minocycline Extended-Release Tablets are used for:

Treating certain types of moderate to severe acne. It may also be used for other conditions as determined by your doctor.


Minocycline Extended-Release Tablets are a tetracycline antibiotic. It works by slowing the growth of certain bacteria, which allows the body's immune system to kill them.


Do NOT use Minocycline Extended-Release Tablets if:


  • you are allergic to any ingredient in Minocycline Extended-Release Tablets or to tetracycline antibiotics (eg, doxycycline)

  • you are taking acitretin, isotretinoin, a live oral typhoid vaccine, methoxyflurane, or a penicillin (eg, amoxicillin)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Minocycline Extended-Release Tablets:


Some medical conditions may interact with Minocycline Extended-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of vision problems

  • if you have asthma, kidney or liver problems, or an autoimmune disorder (eg, lupus)

Some MEDICINES MAY INTERACT with Minocycline Extended-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Acitretin or isotretinoin because the risk of increased pressure in the brain may be increased

  • Methoxyflurane because serious and sometimes fatal kidney problems may occur

  • Aluminum salts (eg, aluminum carbonate) because they may decrease Minocycline Extended-Release Tablets's effectiveness

  • Anticoagulants (eg, warfarin), digoxin, or methotrexate because the risk of their side effects may be increased by Minocycline Extended-Release Tablets

  • Live oral typhoid vaccine, oral contraceptives (birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Minocycline Extended-Release Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Minocycline Extended-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Minocycline Extended-Release Tablets:


Use Minocycline Extended-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Minocycline Extended-Release Tablets. Talk to your pharmacist if you have questions about this information.

  • Take Minocycline Extended-Release Tablets by mouth with or without food. Taking Minocycline Extended-Release Tablets with food or milk may decrease stomach upset. However, certain foods and milk may bind with Minocycline Extended-Release Tablets, preventing its full absorption. Discuss any questions or concerns with your doctor.

  • Swallow Minocycline Extended-Release Tablets whole. Do not break, crush, or chew before swallowing.

  • Take Minocycline Extended-Release Tablets with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Minocycline Extended-Release Tablets.

  • Do not take medicines that have aluminum, magnesium, calcium, or zinc (eg, multivitamins, antacids, quinapril), bismuth, or urinary alkalinizers (eg, sodium bicarbonate) in them within 2 hours before or after you take Minocycline Extended-Release Tablets.

  • Do not take medicines that have iron (eg, ferrous sulfate) in them within 3 hours before or 2 hours after taking Minocycline Extended-Release Tablets. If you need to take iron, check with your doctor about the right type of iron to take along with Minocycline Extended-Release Tablets.

  • Minocycline Extended-Release Tablets works best if it is taken at the same time each day.

  • Do not miss any doses. If you miss a dose of Minocycline Extended-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Minocycline Extended-Release Tablets.



Important safety information:


  • Minocycline Extended-Release Tablets may cause dizziness, lightheadedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Minocycline Extended-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Minocycline Extended-Release Tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Minocycline Extended-Release Tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.

  • Tell your doctor or dentist that you take Minocycline Extended-Release Tablets before you receive any medical or dental care, emergency care, or surgery.

  • Be sure to use Minocycline Extended-Release Tablets for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.

  • Long-term or repeated use of Minocycline Extended-Release Tablets may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.

  • Do not switch between Minocycline Extended-Release Tablets and other types of minocycline without checking with your doctor.

  • Do NOT take more than the recommended dose or take for longer than 12 weeks without checking with your doctor.

  • Women who are able to become pregnant should always use an effective method of birth control while using Minocycline Extended-Release Tablets. Talk with your doctor if you have questions about using birth control.

  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Minocycline Extended-Release Tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms).

  • Men who take Minocycline Extended-Release Tablets should always use a condom when having sex with a woman who may become pregnant. Do this for as long as you take Minocycline Extended-Release Tablets.

  • Minocycline Extended-Release Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Minocycline Extended-Release Tablets.

  • Lab tests, including eye exams, liver and kidney function, or complete blood cell counts, may be performed while you use Minocycline Extended-Release Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Minocycline Extended-Release Tablets should be used with extreme caution in CHILDREN between 8 and 12 years old; safety and effectiveness in these children have not been confirmed.

  • Minocycline Extended-Release Tablets should not be used in CHILDREN younger than 8 years old; it may discolor or damage their teeth.

  • PREGNANCY and BREAST-FEEDING: Minocycline Extended-Release Tablets has been shown to cause harm to the fetus. Do not become pregnant while you are taking it. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Minocycline Extended-Release Tablets while you are pregnant. Minocycline Extended-Release Tablets are found in breast milk. Do not breast-feed while taking Minocycline Extended-Release Tablets.


Possible side effects of Minocycline Extended-Release Tablets:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dizziness; lightheadedness; mild headache or diarrhea; nausea; tiredness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stool; blurred vision; change in amount of urine produced; changes in color of skin, teeth, or gums; dark urine; decreased hearing; fever; joint aches or pain; muscle pain or weakness; red, swollen, blistered, or peeling skin; severe or persistent headache, diarrhea, or tiredness; stomach cramps or pain; symptoms of pancreatitis (eg, severe stomach or back pain with or without nausea or vomiting); unusual bruising or bleeding; unusual tiredness or weakness; vaginal irritation or discharge; vision changes; yellowing of the eyes or skin.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Minocycline Extended-Release Tablets:

Store Minocycline Extended-Release Tablets at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Minocycline Extended-Release Tablets out of the reach of children and away from pets.


General information:


  • If you have any questions about Minocycline Extended-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.

  • Minocycline Extended-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Minocycline Extended-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Minocycline resources


  • Minocycline Dosage
  • Minocycline Use in Pregnancy & Breastfeeding
  • Drug Images
  • Minocycline Drug Interactions
  • Minocycline Support Group
  • 84 Reviews for Minocycline - Add your own review/rating


Compare Minocycline with other medications


  • Acne
  • Actinomycosis
  • Bacterial Infection
  • Bullous Pemphigoid
  • Meningitis, Meningococcal
  • Ocular Rosacea
  • Pemphigoid
  • Pemphigus
  • Periodontitis
  • Rheumatoid Arthritis
  • Rosacea
  • Skin and Structure Infection
  • Skin Infection

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