Generic Name: aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide (a LOO min um hye DROX ide, ASP rin, KAL cee um KAR bo nate, mag NEE see um hye DROX ide)
Brand names: Arthritis Pain Formula, Ascriptin, Ascriptin Maximum Strength, Aspirin Buffered, Magnaprin, Aspir-Mox, Aspir-Mox IB
What is aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide?
Aluminum, calcium, and magnesium are naturally occurring minerals that are used antacids.
Aspirin is a salicylate (sa-LIS-il-ate) and a non-steroidal anti-inflammatory drug (NSAID). Aspirin works by reducing substances in the body that cause pain, fever, and inflammation.
The combination of aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide is used to treat headache, toothache, menstrual pain, and minor aches and pains caused by arthritis or the common cold.
The antacids in this combination medicine help prevent heartburn or stomach discomfort caused by the aspirin contained in the medicine.
Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide is sometimes used to prevent blood clots that may lead to heart attack or stroke. Aspirin should be used for cardiovascular conditions only under the supervision of a doctor.
Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide may also be used for purposes not listed in this medication guide.
What is the most important information I should know about aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide?
Do not take aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide during the last 3 months of pregnancy. It may harm the unborn baby. You should not use this medication if you are allergic to aluminum hydroxide, aspirin, calcium carbonate, or magnesium hydroxide, or if you are allergic to an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others. You should not use this medication if you have a recent history of stomach or intestinal bleeding, a bleeding disorder, vitamin K deficiency, low levels of platelets in your blood, any severe active bleeding, or if you are also using ketorolac (Toradol) or mifepristone (Mifeprex).
Ask a doctor or pharmacist if it is safe for you to take this medication if you have a history of stomach ulcer or other disorder, or if you have asthma, allergies, head injury, heart disease, high blood pressure, kidney or liver disease, diabetes, gout, nasal polyps, fever and headache with neck stiffness, an enzyme deficiency (such as G6PD), if you have recently received a live vaccine, if you are 60 or older, if you have high levels of calcium or magnesium in your blood, or if you drink more than three alcoholic beverages per day.
Aspirin may cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking this medication, especially in older adults.
Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.
There are many other drugs that can interact with aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
If you are taking this medicine to prevent heart attack or stroke, avoid also taking ibuprofen (Advil, Motrin). Ibuprofen may make aspirin less effective in protecting your heart and blood vessels. This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children.
What should I discuss with my healthcare provider before taking aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide?
You should not use this medication if you are allergic to aluminum hydroxide, aspirin, calcium carbonate, or magnesium hydroxide, or if you have:
a recent history of stomach or intestinal bleeding;
a bleeding or blood clotting disorder such as hemophilia;
vitamin K deficiency;
low levels of platelets in your blood;
severe active bleeding;
an allergy to an NSAID (non-steroidal anti-inflammatory drug) such as Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others; or
if you are also using ketorolac (Toradol) or mifepristone (Mifeprex).
Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:
a history of stomach ulcer, heartburn, or other stomach disorder;
asthma or seasonal allergies;
a head injury;
a headache with fever, vomiting, neck stiffness, and increased sensitivity to light;
heart disease, high blood pressure;
kidney or liver disease;
diabetes;
gout;
high levels of calcium or magnesium in your blood;
nasal polyps;
an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);
if you have recently received a live vaccine such as varicella (chickenpox), H1N1 influenza, or nasal flu vaccine;
if you are 60 years or older; or
if you drink more than three alcoholic beverages per day.
Aspirin can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide. Do not take aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide during the last 3 months of pregnancy. It may harm the unborn baby. Aspirin may be harmful to an unborn baby's heart, and may also reduce birth weight or have other dangerous effects. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. This medication should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children.
How should I take aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Take this medicine with a full glass of water. Take this medicine with food or milk if it upsets your stomach.
Avoid lying down for at least 10 minutes after taking this medication, to reduce the risk of heartburn or upset stomach.
Do not take this medication for longer than 10 days to treat pain, or for longer than 3 days to treat fever. Talk with your doctor if your symptoms do not improve or if you have worsening pain or any new symptoms.
This medication can cause false results with certain lab tests for glucose (sugar) in the urine. Tell any doctor who treats you that you are using this medicine.
If you need surgery, tell the surgeon ahead of time that you are using aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide. You may need to stop using the medicine for a short time. Store at room temperature away from moisture, heat, and light. Throw away the medication if you smell a strong vinegar odor in the bottle. The medicine may no longer be effective.
See also: Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide dosage (in more detail)
What happens if I miss a dose?
Since aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include burning or pain in your throat, severe heartburn, mood changes, confusion, ringing in your ears, rapid breathing, seizure, or fainting.
What should I avoid while taking aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide?
Avoid drinking alcohol. It may increase your risk of stomach bleeding.
Avoid taking other medicines within 2 hours before or after you take aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide. The antacids contained in this medicine can make it harder for your body to absorb other medicines, especially antibiotics.
Ask a doctor or pharmacist before using any other cold, allergy, or pain medicine. Aspirin is contained in many combination medicines. Taking certain products together can cause you to get too much aspirin. Check the label to see if a medicine contains aspirin. Avoid taking any other NSAID while you are taking aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide. NSAIDs include ibuprofen (Motrin, Advil), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn, Naprelan, Treximet), piroxicam (Feldene), and others.
Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide and call your doctor at once if you have a serious side effect such as:
weakness or fainting;
black, bloody, or tarry stools;
coughing up blood or vomit that looks like coffee grounds;
severe or worsening stomach pain;
sudden numbness or weakness, especially on one side of the body;
sudden severe headache, confusion, problems with vision, speech, or balance;
urinating less than usual or not at all;
easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
redness, swelling, or increasing pain;
hearing loss, ringing in your ears; or
nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
mild heartburn;
mild nausea, upset stomach; or
diarrhea, stomach cramps.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide Dosing Information
Usual Adult Dose for Ankylosing Spondylitis:
For treatment of inflammatory diseases such as ankylosing spondylitis, osteoarthritis, rheumatoid arthritis, and SLE-associated arthritis and pleurisy:
Initial: 2.4 to 3.6 g (aspirin) per day orally in equally divided doses.
Maintenance: 3.6 to 5.4 g (aspirin) per day orally in equally divided doses; higher dosages may be necessary in some cases.
Serum salicylate levels may be useful in guiding therapeutic decisions regarding dosage titration. Serum salicylate levels of 150 to 300 mcg/mL are associated with anti-inflammatory response. However, the incidence of toxicity increases with salicylate levels > 200 mcg/mL.
Usual Adult Dose for Osteoarthritis:
For treatment of inflammatory diseases such as ankylosing spondylitis, osteoarthritis, rheumatoid arthritis, and SLE-associated arthritis and pleurisy:
Initial: 2.4 to 3.6 g (aspirin) per day orally in equally divided doses.
Maintenance: 3.6 to 5.4 g (aspirin) per day orally in equally divided doses; higher dosages may be necessary in some cases.
Serum salicylate levels may be useful in guiding therapeutic decisions regarding dosage titration. Serum salicylate levels of 150 to 300 mcg/mL are associated with anti-inflammatory response. However, the incidence of toxicity increases with salicylate levels > 200 mcg/mL.
Usual Adult Dose for Rheumatoid Arthritis:
For treatment of inflammatory diseases such as ankylosing spondylitis, osteoarthritis, rheumatoid arthritis, and SLE-associated arthritis and pleurisy:
Initial: 2.4 to 3.6 g (aspirin) per day orally in equally divided doses.
Maintenance: 3.6 to 5.4 g (aspirin) per day orally in equally divided doses; higher dosages may be necessary in some cases.
Serum salicylate levels may be useful in guiding therapeutic decisions regarding dosage titration. Serum salicylate levels of 150 to 300 mcg/mL are associated with anti-inflammatory response. However, the incidence of toxicity increases with salicylate levels > 200 mcg/mL.
Usual Adult Dose for Systemic Lupus Erythematosus:
For treatment of inflammatory diseases such as ankylosing spondylitis, osteoarthritis, rheumatoid arthritis, and SLE-associated arthritis and pleurisy:
Initial: 2.4 to 3.6 g (aspirin) per day orally in equally divided doses.
Maintenance: 3.6 to 5.4 g (aspirin) per day orally in equally divided doses; higher dosages may be necessary in some cases.
Serum salicylate levels may be useful in guiding therapeutic decisions regarding dosage titration. Serum salicylate levels of 150 to 300 mcg/mL are associated with anti-inflammatory response. However, the incidence of toxicity increases with salicylate levels > 200 mcg/mL.
Usual Adult Dose for Fever:
325 to 650 mg (aspirin) orally every 4 hours as needed, not to exceed 4 g/day.
Usual Adult Dose for Pain:
325 to 650 mg (aspirin) orally every 4 hours as needed, not to exceed 4 g/day.
Usual Adult Dose for Rheumatic Fever:
80 mg/kg (aspirin) per day orally in 4 equally divided doses, up to 6.5 g/day.
Dosage may be adjusted according to patient response, tolerance, and serum salicylate levels (therapeutic range = 250 to 400 mcg/mL for rheumatic fever). Generally after 1 to 2 weeks, the dosage is decreased to approximately 60 to 70 mg/kg/day and given for an additional 1 to 6 weeks or longer if necessary, then gradually withdrawn over 1 to 2 weeks. An appropriate course of antibiotic therapy should be initiated at the time of diagnosis of rheumatic fever.
Usual Adult Dose for Myocardial Infarction:
1/2 to 1 regular-strength tablet orally once a day beginning as soon as an acute myocardial infarction is suspected and continuing for 30 days. Long-term aspirin therapy for secondary prevention is recommended after 30 days.
Usual Adult Dose for Ischemic Stroke:
1/2 to 1 regular-strength tablet orally once a day beginning within 48 hours of the onset of stroke and continuing for 2 to 4 weeks. Long-term aspirin therapy for secondary prevention is recommended after 2 to 4 weeks.
Usual Adult Dose for Angina Pectoris:
1/2 to 1 regular-strength tablet orally once a day beginning as soon as unstable angina is diagnosed and continuing indefinitely.
Usual Adult Dose for Angina Pectoris Prophylaxis:
1/2 to 1 regular-strength tablet orally once a day, continued indefinitely.
Usual Adult Dose for Thromboembolic Stroke Prophylaxis:
1/2 to 1 regular-strength tablet orally once a day, continued indefinitely.
Usual Adult Dose for Myocardial Infarction -- Prophylaxis:
1/2 to 1 regular-strength tablet orally once a day, continued indefinitely.
Usual Adult Dose for Ischemic Stroke -- Prophylaxis:
1/2 to 1 regular-strength tablet orally once a day, continued indefinitely.
Usual Adult Dose for Revascularization Procedures -- Prophylaxis:
For coronary artery bypass graft (CABG): 1 regular-strength tablet orally once a day beginning 6 hours after the procedure and continuing for 1 year or indefinitely as needed.
For percutaneous transluminal coronary angiography (PTCA): 1 regular-strength tablet orally once 2 hours prior to procedure, then 1/2 to 1 regular-strength tablet orally once a day indefinitely.
For carotid endarterectomy: 1/2 regular-strength tablet orally once a day up to 1 extra-strength tablet or 2 regular-strength tablets orally twice a day beginning prior to surgery and continuing indefinitely.
Usual Pediatric Dose for Fever:
2 to 11 years: 10 to 15 mg/kg (aspirin) orally every 4 to 6 hours as needed, not to exceed 4 g/day.
>=12 years: 325 to 650 mg (aspirin) orally every 4 hours as needed, not to exceed 4 g/day.
Usual Pediatric Dose for Pain:
2 to 11 years: 10 to 15 mg/kg (aspirin) orally every 4 to 6 hours as needed, not to exceed 4 g/day.
>=12 years: 325 to 650 mg (aspirin) orally every 4 hours as needed, not to exceed 4 g/day.
Usual Pediatric Dose for Juvenile Rheumatoid Arthritis:
2 to 11 years or Initial: 60 to 90 mg/kg (aspirin) per day orally in equally divided doses.
Maintenance: 80 to 100 mg/kg (aspirin) per day orally in equally divided doses; higher dosages, up to 130 mg/kg/day, may be necessary in some cases, not to exceed 5.4 g/day.
>=12 years or >25 kg:
Initial: 2.4 to 3.6 g (aspirin) per day orally in equally divided doses.
Maintenance: 3.6 to 5.4 g (aspirin) per day orally in equally divided doses; higher dosages may be necessary in some cases.
Serum salicylate levels may be useful in guiding therapeutic decisions regarding dosage titration. Serum salicylate levels of 150 to 300 mcg/mL are associated with anti-inflammatory response. However, the incidence of toxicity increases with salicylate levels > 200 mcg/mL.
Usual Pediatric Dose for Kawasaki Disease:
Initial (acute febrile period): 80 to 100 mg/kg (aspirin) per day orally in 4 equally divided doses every 4 to 6 hours.
Maintenance (post-febrile period): 3 to 5 mg/kg (aspirin) orally once daily. Patients without coronary artery abnormalities should continue low-dose aspirin for 6 to 8 weeks or until ESR and platelet count are normal. Patients with coronary artery abnormalities should continue low-dose aspirin therapy indefinitely.
Usual Pediatric Dose for Rheumatic Fever:
90 to 130 mg/kg (aspirin) per day in equally divided doses every 4 to 6 hours, up to 6.5 mg/day.
Dosage may be adjusted according to patient response, tolerance, and serum salicylate levels (therapeutic range = 250 to 400 mcg/mL for rheumatic fever). Generally after 1 to 2 weeks, the dosage is decreased to approximately 60 to 70 mg/kg/day and given for an additional 1 to 6 weeks or longer if necessary, then gradually withdrawn over 1 to 2 weeks. An appropriate course of antibiotic therapy should be initiated at the time of diagnosis of rheumatic fever.
Usual Pediatric Dose for Prosthetic Heart Valves -- Mechanical Valves:
6 to 20 mg/kg (aspirin) orally once daily.
Aspirin may be administered in combination with an oral anticoagulant if systemic embolism occurs despite achieving target INR levels, or it may be used with low-dose oral anticoagulant and dipyridamole when full-dose warfarin is contraindicated.
What other drugs will affect aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide?
If you are taking this medicine to prevent heart attack or stroke, avoid also taking ibuprofen (Advil, Motrin). Ibuprofen may make aspirin less effective in protecting your heart and blood vessels. If you must use both medications, take the ibuprofen at least 8 hours before or 30 minutes after you take aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide.
Many drugs can interact with aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide. Below is just a partial list. Tell your doctor if you are using:
acetazolamide (Diamox);
digoxin (Lanoxin, Lanoxicaps);
diltiazem (Cartia, Cardizem);
dipyridamole (Persantine);
a diuretic (water pill);
ginkgo biloba;
methotrexate (Rheumatrex, Trexall);
mycophenolate (CellCept) or mycophenolic acid (Myfortic);
pemetrexed (Alimta);
valproic acid (Depakene, Stavzor);
an antibiotic such as ciprofloxacin (Cipro), doxycycline (Doryx, Oracea, Periostat, Vibramycin), gemifloxacin (Factive), levofloxacin (Levaquin), minocycline (Dynacin, Minocin, Solodyn), moxifloxacin (Avelox), norfloxacin (Noroxin), ofloxacin (Floxin), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap);
an antidepressant such as citalopram (Celexa), fluoxetine (Prozac, Sarafem, Symbyax), paroxetine (Paxil), or sertraline (Zoloft), and others;
blood pressure medication such as atenolol (Tenormin, Tenoretic), benazepril (Lotensin), captopril (Capoten), carvedilol (Coreg), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), ramipril (Altace), sotalol (Betapace), and others;
a blood thinner such as warfarin (Coumadin, Jantoven);
citrate salts (Bicitra, Citracal, Cytra-K, Oracit, Polycitra, Urocit);
gout medication such as allopurinol (Zyloprim) or probenecid (Benemid);
medication to treat osteoporosis or Paget's disease, such as alendronate (Fosamax), etidronate (Didronel), ibandronate (Boniva), pamidronate (Aredia), risedronate (Actonel, Atelvia), or zoledronic acid (Reclast, Zometa);
an oral diabetes medication such as glipizide (Glucotrol, Metaglip), glyburide (DiaBeta, Micronase, Glucovance), and others; or
steroids (prednisone and others).
This list is not complete and there are many other drugs that can interact with aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
More aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide resources
- Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide Dosage
- Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide Drug Interactions
- Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide Support Group
- 1 Review for Aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide - Add your own review/rating
Compare aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide with other medications
- Angina
- Angina Pectoris Prophylaxis
- Ankylosing Spondylitis
- Fever
- Heart Attack
- Ischemic Stroke
- Ischemic Stroke, Prophylaxis
- Juvenile Rheumatoid Arthritis
- Kawasaki Disease
- Myocardial Infarction, Prophylaxis
- Osteoarthritis
- Pain
- Prosthetic Heart Valves, Mechanical Valves
- Revascularization Procedures, Prophylaxis
- Rheumatic Fever
- Rheumatoid Arthritis
- Systemic Lupus Erythematosus
- Thromboembolic Stroke Prophylaxis
Where can I get more information?
- Your pharmacist can provide more information about aluminum hydroxide, aspirin, calcium carbonate, and magnesium hydroxide.
No comments:
Post a Comment